Bibliography: Science Regarding Treatment-Based Approaches in Autism by Elizabeth Mumper, MD, Teresa Binstock, and Jane Johnson

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BIBLIOGRAPHY
Bibliography:
Science regarding Treatment-Based Approaches in Autism
by Elizabeth Mumper, MD, Teresa Binstock, Jane Johnson
The authors wish to acknowledge the help of colleagues at the Autism Research Institute for their work in contributing to this bibliography. Autism is a whole-body condition, and there may be multiple etiologies that culminate in common pathways that result in the pattern of behaviors we describe as “autism.” “Autism” as a label does not tell us about the underlying issues that affect the patient, most importantly, immune dysregulation, intestinal inflammation, metabolic abnormalities, neuroinflammation, and other pathologies that have bearing upon cognitive function. When we understand the medical issues, we can begin to most efficiently help the affected individual. The science that substantiates medical issues in autism is sound and has been presented by scientists in the disciplines of gastroenterology, immunology, endocrinology, neuropathology, and toxicology and published in peer-reviewed literature. As a resource for all who are interested in the science that substantiates the Defeat Autism Now! and other treatment-based approaches [Editor’s note: as indicated in the previous article in this magazine], we present following a comprehensive but incomplete bibliography of scientific studies related to autism.
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High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased K (m)): relevance to genetic disease and polymorphisms. Am J Clin Nutr. 2002 Apr;75(4):616-58. Amminger GP, Berger GE, Schafer MR, Klier C, Friedrich MH, Feucht M. Omega-3 Fatty Acids Supplementation in Children with Autism: A Double-blind Randomized, Placebocontrolled Pilot Study. Biol Psychiatry. 2006 Aug 22; [Epub ahead of print]. Andersen IM, Kaczmarska J, McGrew SG, Malow BA. Melatonin for Insomnia in Children With Autism Spectrum Disorders. J Child Neurol. 2008 Jan 8. Arnold GL et al. Plasma amino acids profiles in children with autism: potential risk of nutritional deficiencies. J Autism Dev Disord 2003 33(4):449-54. PMID: 12959424. Ashwood P et al. Intestinal lymphocyte populations in children with regressive autism: evidence for extensive mucosal immunopathology. J Clin Immunol. 2003 Nov;23(6):504-17. PMID: 15031638. Ashwood P, Anthony A, Pellicer AA, Torrente F, WalkerSmith JA, Wakefield AJ. Intestinal lymphocyte populations in children with regressive autism: evidence for extensive mucosal immunopathology. J Clin Immunol. 2003 Nov;23(6):504-17. Ashwood P, Anthony A, Torrente F, Wakefield AJ. Spontaneous mucosal lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms: mucosal immune activation and reduced counter regulatory interleukin-10. J Clin Immunol. 2004 Nov;24(6):664-73. Ashwood P, Van de Water J. Is autism an autoimmune disease? Autoimmun Rev. 2004 Nov;3(7-8):557-62. Ashwood P, Wakefield AJ. Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms. J Neuroimmunol. 2006 Apr;173(1-2):126-34. Ashwood P, Willis S, Van de Water J. The immune response in autism: a new frontier for autism research. J Leuk Biol. 2006 Jul:80;1-15. Balzola F, Barbon V, Repici A, Rizzetto M. Panenteric IBDlike disease in a patient with regressive autism shown for the first time by the wireless capsule enteroscopy: another piece in the jigsaw of this gut-brain syndrome? Am J Gastro. 2005; 979-981. Balzola F, Daniela C, Repici A, Barbon V, Sapino A, Barbera C, Calvo PL, Gandione M, Rigardetto R, Rizzetto M. Autistic enterocolitis: confirmation of a new inflammatory bowel disease in an Italian cohort of patients. Gastroenterology. 2005;128:Suppl.2;A-303. Balzola F, et al. Autistic Enterocolitis in childhood: the early evidence of the later Crohn’s disease in autistic adulthood? Gastroenterology April 2007 Vol 132, N. 4, suppl 2 W 1100 A 660 Balzola F, et al. Beneficial behavioural effects of IBD therapy and gluten/casein-free diet in an Italian cohort of patients with autistic enterocolitis followed over one year. Gastroenterology, April 2006 Vol 130 Number 4 suppl. 2 S1364 A-21. Belluzzi A, Brignola C, Campieri M, Pera A, Boschi S, Miglioli M. Effect of an enteric-coated fish-oil preparation on relapses in Crohn’s disease. N Engl J Med. 1996 Jun 13;334(24):1557-60. Biller JA, Katz AJ, Flores AF, Buie TM, Gorbach SL. Treatment of recurrent Clostridium difficile colitis with Lactobacillus GG. J Pediatr Gastroenterol Nutr. 1995 Aug;21(2):224-6. Boris M, Goldblatt A, Galanko J, James J. Association of MTHFR gene variants with autism. J Am Phys Surg. 2004;9(4)106-8. Boris M, Kaiser C, Goldblatt A, Elice MW, Edelson SM, Feinstein DL. Effect of Pioglitazone treatment on behavioral symptoms in autistic children. J Neuroinflammation. 2007 Jan 5;4:3. Bradstreet JJ, smith S, Granpeesheh D, El_Dahr, JM, Rossignol D. Spironolactone might be a desirable immunologic and hormonal intervention in autism spectrum disorders. Med Hypothesis. 2006 Dec 4. Bradstreet JJ, El Dahr JM, Anthony A, Kartzinel JJ, Wakefield, AJ. Detection of measles virus genomic RNA in cerebrospinal fluid of children with regressive autism: a report of three cases. J Am Phys Surg. 2004:9 (2): 38-45. Braunschweig D, Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Autism: Maternally derived antibodies specific for fetal brain proteins. Neurotoxicology. 2007 Nov 6. Buts JP, De Keyser N, De Raedemaeker L. Saccharomyces boulardii enhances rat intestinal enzyme expression by endoluminal release of polyamines. Pediatr Res. 1994 Oct;36(4):522-7. Buts JP, De Keyser N. Effects of Saccharomyces boulardii on intestinal mucosa. Dig Dis Sci. 2006 Aug;51(8):1485-92. Buts JP, De Keyser N, Marandi S, Hermans D, Sokal EM, Chae YH, Lambotte L, Chanteux H, Tulkens PM. Saccharomyces boulardii upgrades cellular adaptation after proximal enterectomy in rats. Gut. 1999 Jul;45(1):89-96.
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Reprinted with permission of The Autism File www.autismfile.com
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Reprinted with permission of The Autism File www.autismfile.com

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