Dr. Arthur Krigsman Pharmaceutical Agents of Interest in the Development of Clinical Treatment Trials of Autism-Associated Enterocolitis

Autism associated enterocolitis has been shown to be a unique variant of inflammatory bowel disease, separate and distinct from other known IBDs. However, striking similarities to Crohn's disease exist in the clinical presentation, anatomic distribution, histologic findings, cytokine profiles, and observed responses to pharmaceutical agents. These similarities will be discussed and pharmaceutical agents that are best candidates for clinical treatment trials will be presented.

Arthur Krigsman, MD is a pediatrician and board-certifi ed pediatric gastroenterologist, and an assistant professor of pediatrics at New York University School of Medicine in New York. He has extensive experience in the evaluation and treatment of gastrointestinal disease in children with autism spectrum disorder and participates in the growing fi eld of research designed to better understand GI disease in this group of children. He has presented his fi ndings in peer-reviewed journals and has shared his experience at scientifi c and lay meetings, and at a congressional hearing dealing with autism and its possible causes.

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