Dr. Richard Frye The Efficacy of Traditional and Non-traditional Treatments on Seizures in Individuals with Autism Spectrum Disorder‏

To better understand the characteristics of seizures in individuals with autism spectrum disorder (ASD), we developed a 737-question online Web-based survey. The survey was designed to better understand the age of onset, gender ratio, associated medical conditions and types of seizures characteristic of seizures in individuals with ASD. In addition, we aimed to understand the relationship between seizures and developmental regression and the effect of traditional and non-traditional antiepileptic treatments on seizures, behavior and development in children with ASD and seizures. Each treatment was rated for effect on seizures, sleep, expressive and receptive language, verbal and nonverbal communication, stereotypic and repetitive behavior, rigidity, flexibility and adaptability, hyperactivity, attention and mood. In addition, the frequency of side effects was also queried. Over 500 individuals completed the survey advertised on the Autism Research Institute website. Overall, the gender ratio, associated medical conditions and proportion of children demonstrating regression was similar in the surveyed population as compared to general ASD population...

Richard E. Frye, MD, PhD received his MD and PhD from Georgetown University. He completed his pediatric residency training at University of Miami and child neurology residency training at Children's Hospital Boston. Following residency Dr. Frye completed a fellowship in behavioral neurology and learning disabilities at Children's Hospital Boston. Dr. Frye is also funded by the National Institutes of Health to study brain function in individuals with dyslexia and is the medical director of the University of Texas medically-based autism clinic.

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