Intestinal Microbial Ecology and Autistic Gastrointestinal Problems

The gut bacteria of children with autism was compared with typical children using pyrosequencing of stool samples. We observed that the gut microflora in healthy children was more diverse and had a higher number of unique phylotypes than in autistic children. At the phylum level, children with autism had more Verrucomcrobia, and less Proteobacteria. At the genus level, children with autism had high amounts of Akkermansia, and less Oscilibacter, Prevotella, and Paraprevotella.

James B. Adams, PhD, PhD

James B. Adams, Ph.D., is a President's Professor at Arizona State University, where he directs the ASU Autism/Asperger's Research Program. His research focuses on the medical causes of autism and how to treat it, including nutrition, toxic metals, gut bacteria, and seizures.

Rosa Krajmalnik-Brown, PhD

Rosa Krajmalnik-Brown, Ph.D, is an assistant professor at Arizona State University. Her research includes evaluation of gut bacteria in obesity and in autism.