Hemp, Endocannabinoids and Neuro-Endo-Immune Poise

Hemp-derived cannabidiol (CBD) has proven to be a useful addition to protocols for conditions involving neuroinflammation, but its balancing effects extend deeply into many homeostatic (balancing) mechanisms and act in many ways like an adaptogen.  Cannabinoid receptors extend throughout the body and the most notable sites of impact are 1) neurological, where it quenches neuroinflammation and helps balance GABA and glutamate; 2) endocrine, where CB2 receptors play into estrogen/progesterone balance and endometrial function; 3) and immune, where CB2 receptors help balance inflammatory response.  All three of these systems have overlaps and cross-controls that make them interdependent and a balance of these (called Neuro-Endo-Immune Poise) is core to robust health and ability to adapt to stress.  Hemp CBD’s ability to enhance Neuro-Endo-Immune Poise is at the cores of its broad range of beneficial effects on health.  We will review the latest research on these diverse functions, new data on uptake of different delivery systems for hemp extracts, and how to use high-bioavailability products in protocols.


Christopher Shade, PhD

Christopher Shade, PhD, earned a PhD from the University of Illinois, where he studied the environmental and analytical chemistries of mercury as well as advanced aquatic chemistry. During his PhD work, Dr. Shade patented analytical technology for mercury speciation analysis and later founded Quicksilver Scientific, LLC, in order to commercialize this technology. Shortly after starting Quicksilver Scientific, Dr. Shade turned his focus to the human aspects of mercury exposure/toxicity and the human detoxification system. He has since developed a system of products to remove metallic and organic toxins by upregulation of innate detoxification biochemistry. He has also focused on development of advanced phospholipid-based delivery systems for nutraceuticals.